Endocrine Abstracts

Introduction: Patients with primary adrenal insufficiency (PAI) require lifelong corticoids replacement and they are at risk of therapy-related osteoporosis and cardiovascular complications.Objectives: Determine the prevalence of cardiovascular risk factors, osteoporosis, and other toxicities related with corticoids treatment.Material and methods: Retrospective, descriptive study in patients with PAI follow up in our service during...

Transsphenoidal adenomectomy (TSA) is the recommended primary therapy in most patients with acromegaly and results in remission for majority of microadenomas and a proportion of macroadenomas depending on extent of surgically accessible disease. Acromegaly is associated with significant mortality and morbidity, hence a combination of treatment modalities may be needed to achieve disease control.Methods: A retrospective casenotes review was conducted and ...

Introduction: Dyslipidemia (DL) in diabetic patients is frequently undertreated. Even when cLDL targets have not been met, treatment remains unchanged despite the availability of alternatives approaches. This is known as therapeutic inertia (TI).The aim of this study was to evaluate the prevalence of TI in lipid management among diabetic patients and to analyse associated factors and possible causes.Material and Methods: Retrospective, cross-sectional st...

Background: Fractures are frequent in patients with chronic renal failure (CRF) with secondary hyperparathyroidism (SHPT) undergoing hemodialysis. Cinacalcet (CT) is a drug used in the reduction of hypercalcemia in these patients that acts through the lintel calcium sensor in the parathyroid gland. Recently, it has been pointed out that CT can reduce fractures in these patients by unknown mechanisms (EVOLVE Trials 2015).Objectives: To evaluate the effect...

Background: Branchial cleft cysts account for almost 20 percent of pediatric neck masses. They are usually present in late childhood or early adulthood, when a previously unrecognized cyst becomes infected. First branchial cleft cysts typically appear on the face near the auricle. Second branchial cleft cysts are the most common and they are usually located just inferior to the angle of the mandible and anterior to the sternocleidomastoid muscle. Third branchial cleft cysts ar...

Introduction: Disease-related malnutrition (DRM) is characterized by the presence of an acute or chronic inflammatory response. The traditional parameters for diagnosis, such as albumin, have failed in their application, forcing a reconsideration of the criteria used for the diagnosis of DRM. The ratio of C-Reactive Protein to prealbumin (CP ratio) allows to assess nutritional changes in relation to the inflammatory environment. The objective of this study is to assess the dia...